PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsLactic acid
Lactic acid
Phexxi, Prismasol (lactic acid) is a small molecule pharmaceutical. Lactic acid was first approved as Prismasol bgk 2/0 in plastic container on 2006-10-25. It is used to treat dermatitis and facial dermatoses in the USA. It is known to target hydroxycarboxylic acid receptor 1.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Combinations
Phexxi, Prismasol (discontinued: Prismasol)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Calcium chloride
+
Dextrose
+
Lactic acid
+
Magnesium chloride
+
Potassium chloride
+
Sodium bicarbonate
+
Sodium chloride
Tradename
Company
Number
Date
Products
PRISMASOL BGK 2/0 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 2/3.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 4/2.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 0/2.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL B22GK 4/0 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
PRISMASOL BK 0/0/1.2 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
PRISMASOL BGK 4/0/1.2 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
Show 8 discontinued
Citric acid
+
Lactic acid
+
Potassium bitartrate
Tradename
Company
Number
Date
Products
PHEXXIEvofem BiosciencesN-208352 RX2020-05-22
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
ammonium lactateANDA2025-07-25
anubis barcelona new evenOTC monograph final2023-09-01
anubismedOTC monograph final2023-09-05
aoao snow bieach intensive for face and bodyC2002632024-10-18
aoao whitening creamC2002632024-10-13
cheongin haejanghwanunapproved drug other2011-02-18
cheongin haewoohwanunapproved drug other2011-02-18
cheongin samrakhwanunapproved drug other2011-02-17
delflexNew Drug Application2025-07-02
dexrazoxaneANDA2024-11-02
Show 59 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
wounds and injuries—D014947T14.8
dry eye syndromes—D015352H04.12
gastroesophageal refluxEFO_0003948D005764K21
hyperkalemia—D006947E87.5
dyspepsiaEFO_0008533D004415K30
dermatitis—D003872L30.9
heart arrestEFO_0009492D006323I46
drug overdose—D062787—
facial dermatoses—D005148—
corneal edemaEFO_1000879D015715H18.20
Show 6 more
Agency Specific
FDA
EMA
Expiration
Code
CITRIC ACID / LACTIC ACID / POTASSIUM BITARTRATE, PHEXXI, EVOFEM INC
2023-05-22NP
Patent Expiration
Patent
Expires
Flag
FDA Information
Citric Acid / Lactic Acid / Potassium Bitartrate, Phexxi, Evofem Inc
105688552033-03-15U-1
113379892033-03-15U-1
114396102033-03-15DS, DP
67062762023-09-06DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07F: Antidiarrheal microorganisms
— A07FA: Antidiarrheal microorganisms
— A07FA01: Lactic acid producing organisms
— A07FA51: Lactic acid producing organisms, combinations
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AD: Organic acids, gynecological
— G01AD01: Lactic acid
HCPCS
No data
Clinical
Clinical Trials
1905 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ContraceptionD003267————1——1
InfectionsD007239EFO_0000544——11——1
Chlamydia infectionsD002690EFO_0007205A74.9—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameLactic acid
INN—
Description
2-hydroxypropanoic acid is a 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. It has a role as a Daphnia magna metabolite and an algal metabolite. It is functionally related to a propionic acid. It is a conjugate acid of a lactate.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(O)C(=O)O
Identifiers
PDB—
CAS-ID50-21-5
RxCUI1314409
ChEMBL IDCHEMBL1200559
ChEBI ID78320
PubChem CID612
DrugBank—
UNII ID—
Target
Agency Approved
No data
Alternate
HCAR1
HCAR1
Organism
Homo sapiens
Gene name
HCAR1
Gene synonyms
GPR104, GPR81, HCA1
NCBI Gene ID
27198
Protein name
hydroxycarboxylic acid receptor 1
Protein synonyms
G protein-coupled receptor 104, G-protein coupled receptor 104, G-protein coupled receptor 81, hydroxy-carboxylic acid receptor 1, lactate receptor 1, T-cell activation G protein-coupled receptor
Uniprot ID
Q9BXC0
Mouse ortholog
Hcar1 (243270)
hydroxycarboxylic acid receptor 1 (B9EJ36)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Phexxi – Evofem Biosciences
Plot placeholder
Mock data
Subscribe for the real data
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Estimated US medical usage
Lactic acid
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 1,065,413 documents
View more details
Safety
Black-box Warning
Black-box warning for: Haloperidol, Haloperidol lactate, Perseris, Prenate enhance, Prenate restore
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
105,386 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use