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AboutPricing
Drug ReportsLactic acid
Lactic acid
Phexxi, Prismasol (lactic acid) is a small molecule pharmaceutical. Lactic acid was first approved as Prismasol bgk 2/0 in plastic container on 2006-10-25. It is used to treat dermatitis and facial dermatoses in the USA. It is known to target hydroxycarboxylic acid receptor 1.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Combinations
Phexxi, Prismasol (discontinued: Prismasol)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Calcium chloride
+
Dextrose
+
Lactic acid
+
Magnesium chloride
+
Potassium chloride
+
Sodium bicarbonate
+
Sodium chloride
Tradename
Company
Number
Date
Products
PRISMASOL BGK 2/0 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 2/3.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 4/2.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL BGK 0/2.5 IN PLASTIC CONTAINERBaxterN-021703 RX2006-10-25
1 products, RLD, RS
PRISMASOL B22GK 4/0 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
PRISMASOL BK 0/0/1.2 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
PRISMASOL BGK 4/0/1.2 IN PLASTIC CONTAINERBaxterN-021703 RX2008-10-10
1 products, RLD, RS
Show 8 discontinued
Citric acid
+
Lactic acid
+
Potassium bitartrate
Tradename
Company
Number
Date
Products
PHEXXIEvofem BiosciencesN-208352 RX2020-05-22
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
ammonium lactateANDA2024-11-20
anubis barcelona new evenOTC monograph final2023-09-01
anubismedOTC monograph final2023-09-05
aoao snow bieach intensive for face and bodyC2002632024-10-18
aoao whitening creamC2002632024-10-13
cheongin haejanghwanunapproved drug other2011-02-18
cheongin haewoohwanunapproved drug other2011-02-18
cheongin samrakhwanunapproved drug other2011-02-17
delflexNew Drug Application2025-03-24
dexrazoxaneANDA2024-11-02
Show 59 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
dermatitis—D003872L30.9
facial dermatoses—D005148—
urination disorders—D014555—
renal tubular acidosis—D000141N25.89
Agency Specific
FDA
EMA
Expiration
Code
CITRIC ACID / LACTIC ACID / POTASSIUM BITARTRATE, PHEXXI, EVOFEM INC
2023-05-22NP
Patent Expiration
Patent
Expires
Flag
FDA Information
Citric Acid / Lactic Acid / Potassium Bitartrate, Phexxi, Evofem Inc
105688552033-03-15U-1
113379892033-03-15U-1
114396102033-03-15DS, DP
67062762023-09-06DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07F: Antidiarrheal microorganisms
— A07FA: Antidiarrheal microorganisms
— A07FA01: Lactic acid producing organisms
— A07FA51: Lactic acid producing organisms, combinations
G: Genito urinary system and sex hormones
— G01: Gynecological antiinfectives and antiseptics
— G01A: Antiinfectives and antiseptics, excl. combinations with corticosteroids
— G01AD: Organic acids, gynecological
— G01AD01: Lactic acid
HCPCS
No data
Clinical
Clinical Trials
1455 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ContraceptionD003267————2——2
InfectionsD007239EFO_0000544——11——1
Chlamydia infectionsD002690EFO_0007205A74.9—11——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameLactic acid
INN—
Description
2-hydroxypropanoic acid is a 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group. It has a role as a Daphnia magna metabolite and an algal metabolite. It is functionally related to a propionic acid. It is a conjugate acid of a lactate.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
CC(O)C(=O)O
Identifiers
PDB—
CAS-ID50-21-5
RxCUI1314409
ChEMBL IDCHEMBL1200559
ChEBI ID78320
PubChem CID612
DrugBank—
UNII ID—
Target
Agency Approved
No data
Alternate
HCAR1
HCAR1
Organism
Homo sapiens
Gene name
HCAR1
Gene synonyms
GPR104, GPR81, HCA1
NCBI Gene ID
27198
Protein name
hydroxycarboxylic acid receptor 1
Protein synonyms
G protein-coupled receptor 104, G-protein coupled receptor 104, G-protein coupled receptor 81, hydroxy-carboxylic acid receptor 1, lactate receptor 1, T-cell activation G protein-coupled receptor
Uniprot ID
Q9BXC0
Mouse ortholog
Hcar1 (243270)
hydroxycarboxylic acid receptor 1 (B9EJ36)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Phexxi – Evofem Biosciences
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Estimated US medical usage
Lactic acid
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,005,104 documents
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Safety
Black-box Warning
Black-box warning for: Haloperidol, Haloperidol lactate, Perseris, Prenate enhance, Prenate restore
Adverse Events
Top Adverse Reactions
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103,488 adverse events reported
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